加入我们

昂阔医药致力于将其日益扩大的管线中的临床前候选药物转化为可以为全球患者带来帮助和希望的创新疗法。

我们的成功与优秀的团队密不可分,期待更多充满热情的优秀人才加入团队。我们拥有中西融合的企业文化,在纽约和上海两地均设有办公室。通过发放股票期权,我们与每位为公司作出贡献的员工共享成功果实。

公司福利

我们致力于打造一支横跨中美的一流团队,我们的团队愿景是通过开发创新药给全球患者提供帮助。在昂阔,我们提供弹性工作制以及有市场竞争力的的薪资,福利。期待您的加入!

  • 有市场竞争力的薪资和福利
  • 员工持股计划
  • 高比例公司匹配缴纳401(k),无等待期 (美国)
  • 健康储蓄账户 (美国)

工作机会

Division
  • Development
  • CMC
  • BD
  • Finance
  • R&D
  • Associate Director / Director, Preclinical Research and Management

    • Division: R&D
    • Location: CN
    • Direct Supervisor: VP, Research

    Position Summary:

    Responsible for overall program management to ensure robust and balanced cross-functional planning, decision-making, implementation, monitoring, and reporting for one or multiple related programs to ensure strong alignment between Research&Development / Business Development/Finance/) and operational execution by the Global Project Team (GPT)

    Capable of reviewing study designs and study reports from collaborators and CRO. Competent in managing the experiment progress and troubleshooting. 

    Be able to both provide strategic vision and guide the team to develop integrated plans for successfully executing the strategy

    Support the development of publications arising from studies and other relevant initiatives

    Highly skilled at meeting management / facilitation

    Responsibilities:

    Project planning

    Work with Project Management to create strategic and operational objectives and integrated tactical plans to drive program goals.  Drive team alignment around these objectives and plans.

    Working with collaborators and CROs to formulate the study design and reports. Capable of troubling shooting ongoing experiments with CROs and provide summary to the line manager on the progress and challenge of individual experiment/project.

    Capable of reviewing research contract/agreement and able to provide bilingual support (Chinese and English) with colleagues in US R&D center

    Ensure the operational deliverables of the project are achieved on or ahead of schedule and within budget such that they meet the desired product profile criteria

    Define and track scope, risks, budget/costs and time, critical path

    Maintain the overall development plans and enterprise portfolio inputs

    Drive team meetings/agendas/minutes/action items including decision and action logs

    Ensures that teams work effectively to move the program forward

    Coordinate preclinical development studies

    Defining strategies, together with the project team, for the early development of PCCs

    Forecasting and tracking on departmental and/or project budget.

    Execution

    Drive new asset discovery projects through engagement of external partners and labs (academic, biotech, CRO), primarily in China, to drive lead discovery and optimization.

    Contribute to design, plan, and execution of all needed preclinical studies 

    Managing the selection and outsourcing of preclinical studies to Contract Research Organizations (CROs) to provide data necessary to support IND and First-in-Human Phase I clinical trial.

    Support external engagements with KOLs/experts to gain input on in-licensing opportunities and pre-clinical / clinical development strategy by ensuring appropriate CDAs, consulting agreements, scope of work, questions, compilation of feedback, timelines, payments, etc.

    Review and validation of study documentation, analysis and discussion about the results, with OnCusp staff, CROs or external experts 

    Writing / updating of the preclinical part of the regulatory documents (IMPD, IND, IB) 

    Manage the transition from preclinical development to Phase I/Proof of Concept (POC) clinical trials

    Managing development issues through close interaction with research and development teammates 

    Enterprise support

    Writing of OnCusp preclinical SOPs

    Support organizational and portfolio planning, SOPs and governance processes, as needed

    Create a safe, open-communication work environment

    Qualifications:

    Advanced degree (Master degree is required and Ph.D. would be a plus.)in relevant biology, biochemistry or related discipline preferred. 

    5+ years of biotechnology experience with drug discovery and development expertise

    Sustained and successful experience with project management working with cross-disciplinary teams; works well across boundaries in a highly matrix-based organization

    Effective in communication skills both verbal and written; listens and understands well

    Proactively recognizes needs and problems, and independently identifies and implements effective steps and solutions

    Strong skills engaging with people from different cultures, backgrounds and perspectives

    Extensive knowledge and experience in project management discipline and its application to drug R&D

    Good oral and written communication skills